Long-term Outcomes of Valve Replacement and Repair: A Systematic Review

The long-term results of valve replacement (VR) and valve repair (VRp) surgeries will be assessed and compared in this thorough analysis, with particular attention paid to mortality, reoperation rates, durability, and quality-of-life indicators. From the beginning until 2024, we systematically searched the PubMed, Cochrane Library, and Embase databases using keywords associated with “valve replacement,” “valve repair,” and “long-term outcomes.” Randomized controlled trials, observational cohorts, and meta-analyses were among the studies that had at least 5 years of follow-up. Case reports, articles written in languages other than English, and research without comparable data were among the exclusion criteria. All-cause mortality, reoperation rate, thromboembolic events, valve durability, and patient-reported outcomes were the main topics of data extraction. When data allowed, meta-analytic comparisons were added to the qualitative synthesis of the evidence. To support evidence-based decision-making for the treatment of valvular heart disease, this review emphasizes the trade-offs between VR and VRp.