Key result
Discontinuous intrarenal venous flow linked to ~5.2-fold higher 1-year adverse cardiac events.
Why the study?
The prognostic significance of intrarenal venous flow patterns relative to invasive hemodynamics in patients with heart failure remains unclear.
Does a discontinuous intrarenal venous flow pattern predict a composite of HF rehospitalization and cardiac death in patients hospitalized for heart failure?
Cohort (n=253)
No
Does a discontinuous intrarenal venous flow pattern predict a composite of HF rehospitalization and cardiac death in patients hospitalized for heart failure?
Hazard Ratio: 5.21 (95% CI 1.81–15)
p-value: p=<0.001
A discontinuous intrarenal venous flow pattern measured by ultrasound is a strong independent predictor of adverse outcomes in heart failure patients, particularly those with a low cardiac index.
Should not yet change heart failure management; leaves open incremental value of intrarenal venous flow assessment.
Background: Intrarenal venous flow (IRVF) patterns assessed by Doppler ultrasonography enable non-invasive assessment of renal venous congestion in patients with heart failure (HF). IRVF patterns have also attracted attention as markers of cardiorenal interactions, but their prognostic significance relative to invasive hemodynamics remains unclear.
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Shingu et al. (2026) conducted a cohort in Heart Failure (n=253). Discontinuous intrarenal venous flow (IRVF) pattern vs. Continuous IRVF pattern was evaluated on Composite of HF rehospitalization and cardiac death within 1 year (HR 5.21, 95% CI 1.81-15.0, p=<0.001). A discontinuous intrarenal venous flow pattern was independently associated with an increased risk of heart failure rehospitalization or cardiac death within 1 year (HR 5.21).
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