Key result
Diabetic cardiomyopathy is linked to ~6-point worse GLS despite preserved LVEF.
Why the study?
The diagnostic significance of global longitudinal strain and tissue Doppler E/e′ for detecting subclinical myocardial damage in type 2 diabetes patients was evaluated.
Do global longitudinal strain (GLS) and E/e' identify subclinical myocardial damage in patients with type 2 diabetes mellitus?
Observational (n=218)
Do global longitudinal strain (GLS) and E/e' identify subclinical myocardial damage in patients with type 2 diabetes mellitus?
Global longitudinal strain (GLS) and tissue Doppler (E/e') can identify subclinical diabetic cardiomyopathy in patients with type 2 diabetes despite preserved ejection fraction.
Reduced GLS may flag subclinical dysfunction despite preserved LVEF; leaves open its prognostic role in cardiomyopathy.
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Ф.А. Икрамова (2026) conducted an observational in Type 2 Diabetes Mellitus (n=218). Diabetic cardiomyopathy vs. Healthy controls was evaluated on Global longitudinal strain (GLS). Patients with diabetic cardiomyopathy had significantly impaired global longitudinal strain (-14.8% vs -20.8%) and elevated E/e' (15.6) compared to controls, despite preserved ejection fraction.
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