Key result
Renal angioplasty yields higher hypertension cure rates in fibromuscular dysplasia than atherosclerosis at ~41% vs. ~23%.
Why the study?
The long-term effects of percutaneous transluminal angioplasty on blood pressure and kidney function in patients with renovascular hypertension were evaluated.
Observational (n=82)
Supports etiology-specific PTA expectations; leaves open comparative efficacy versus medical therapy in renovascular hypertension.
In the present study we report our long-term experience in 82 patients with renovascular hypertension (48 with atherosclerotic stenosis, 34 with fibromuscular dysplasia) who were followed up for a mean observation period of 23.6 months after percutaneous transluminal angioplasty (PTA) of renal artery stenosis. Our results show a highly significant decrease in mean systolic and diastolic blood pressure. Cure rates were slightly higher in patients with fibromuscular dysplasia (41% cured, 47% improved) than in those with atherosclerosis (23% cured, 54% improved). Kidney function significantly improved in patients with cure, remained stable in those with improvement and worsened in cases classified as unimproved. These results document the good long-term effect of PTA on blood pressure and kidney function in patients with renal artery stenosis.
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Greminger et al. (2008) conducted an observational in Renovascular hypertension (n=82). Percutaneous transluminal angioplasty (PTA) was evaluated on Cure and improvement of renovascular hypertension. Percutaneous transluminal angioplasty for renovascular hypertension resulted in cure rates of 41% for patients with fibromuscular dysplasia and 23% for those with atherosclerosis.
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