Key result
Correction of renal artery stenosis cured or improved hypertension in 58% of patients with fibromuscular dysplasia and 29% with atherosclerosis at 12 months.
Why the study?
Does correction of renal artery stenosis improve blood pressure, renal function, and left ventricular morphology in hypertensive patients?
Population
44 hypertensive patients with renal artery stenosis who had no restenosis during 1-year observation, mean…
Design
Cohort
Follow-up
12 months
Authors
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May support etiology-specific revascularization for hypertension; leaves open causal effects on renal function and LV morphology pending RCTs.
Observational (n=61)
Does correction of renal artery stenosis improve blood pressure, renal function, and left ventricular morphology in hypertensive patients?
Correction of renal artery stenosis improves blood pressure control, stabilizes renal function, and promotes regression of left ventricular hypertrophy, with greater antihypertensive efficacy in fibromuscular dysplasia compared to atherosclerotic disease.
Bartosz Symonides (1999) conducted an observational in Hypertension with renal artery stenosis (n=61). Correction of renal artery stenosis (PTRA or surgical treatment) vs. Pre-interventional baseline was evaluated on 24 h SBP, 24 h DBP, creatinine clearance (GFR), urinary albumin excretion (UAE) and LV morphology and mass (LVMI). Correction of renal artery stenosis cured or improved hypertension in 58% of patients with fibromuscular dysplasia and 29% with atherosclerosis at 12 months.
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