Key result
Peritoneal dialysis stabilizes hemodynamics and preserves functional capacity for ~7 months in end-stage ARVC.
Why the study?
The potential benefits of peritoneal dialysis as a palliative option in end-stage heart failure, especially in rare cases like ARVC, are not well described.
Does peritoneal dialysis improve symptoms and quality of life in a patient with end-stage right heart failure and cardiorenal syndrome due to ARVC?
Case Report (n=1)
Does peritoneal dialysis improve symptoms and quality of life in a patient with end-stage right heart failure and cardiorenal syndrome due to ARVC?
Peritoneal dialysis may serve as a viable palliative option to alleviate symptoms and maintain quality of life in patients with end-stage heart failure and kidney injury when other renal replacement therapies fail.
May support PD in refractory right HF with cardiorenal syndrome; leaves open confirmation in prospective studies.
After multiple hospitalisations for diuretic-resistant acute decompensated heart failure (ADHF), an early 60s man with isolated right-sided heart failure due to arrhythmogenic right ventricular cardiomyopathy (ARVC) underwent continuous venovenous haemofiltration without lasting success. His blood urea nitrogen/creatinine ratio was high and renal blood flow and filtration fraction were low, indicative of the underlying cardiorenal dysbalance. Peritoneal dialysis (PD) was initiated because this form of renal replacement therapy provides better haemodynamic stability and a flexible schedule. This allowed the patient to maintain his professional activities and spend time with his family for the subsequent 7 months. Following a diabetic foot infection, his condition worsened, leading to his death. Autopsy showed fibrofatty replacement of the right ventricle and chronic ischaemic nephropathy, without signs of hypertensive or diabetic nephropathy.Although ARVC is rare, this case underscores the potential benefits of PD as a palliative option in end-stage heart failure. Early consideration of PD, particularly when other renal replacement therapies are limited or contraindicated, may alleviate symptoms and enhance quality of life, especially after repeated hospitalisations for heart failure and kidney injury. Collaborative care between cardiologists and nephrologists is essential for optimising management in these patients.
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Janssen et al. (2025) conducted a case report in Acute decompensated heart failure due to arrhythmogenic right ventricular cardiomyopathy (n=1). Peritoneal dialysis was evaluated. Peritoneal dialysis provided hemodynamic stability and allowed a patient with end-stage heart failure due to ARVC to maintain professional and family activities for 7 months.
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