Key result
Cardiopulmonary ultrasound matches chest CT for diagnosing cardiogenic pulmonary edema with ~92% accuracy.
Why the study?
Early diagnosis and treatment of cardiogenic pulmonary edema in heart failure patients is essential, and the value of cardiopulmonary ultrasound for this diagnosis needs evaluation.
Does cardiopulmonary ultrasound (CPUS) provide comparable diagnostic accuracy to chest CT for identifying cardiogenic pulmonary edema in intensive care unit patients with heart failure?
Observational (n=117)
Blinded image interpretation
No
Does cardiopulmonary ultrasound (CPUS) provide comparable diagnostic accuracy to chest CT for identifying cardiogenic pulmonary edema in intensive care unit patients with heart failure?
Effect estimate: Cohen's kappa 0.873 (95% CI 0.782-0.963)
Absolute Event Rate: 92.3% vs 94.9%
p-value: p=<0.001
Cardiopulmonary ultrasound provides a highly accurate, non-invasive bedside alternative to chest CT for diagnosing cardiogenic pulmonary edema in critically ill heart failure patients.
May offer bedside alternative to CT for cardiogenic pulmonary edema in ICU heart failure; leaves open need for larger validation before practice change.
Objective Heart failure (HF) is generally complicated with cardiogenic pulmonary edema (CPE), the early diagnosis and treatment is essential. We aimed to evaluate the effects of cardiopulmonary ultrasound (CPUS) in the diagnosis of CPE in HF patients, to provide reference for the management of HF. Methods HF patients entering The People's Hospital of Guangxi Zhuang Autonomous Region & Guangxi Academy of Medical Sciences intensive care unit (ICU) between March 2025 and July 2026 were included. All patients underwent CPUS and chest computed tomography (CT), and comparison of the detection rates of cardiogenic pulmonary edema between CPUS and CT. Results A total of 117 patients with HF were enrolled in this study. Of the 117 HF patients, 46 were diagnosed with CPE, and 43 were correctly diagnosed by CT, with a diagnostic accuracy of 94.9%, the positive predictive value (PPV) was 93.5%, the negative predictive value (NPV) was 95.8%, the sensitivity was 93.5%, the specificity was 95.8%, the positive likelihood ratio (PLR) was 22, and the negative likelihood ratio (NLR) was 0.07. While 41 were correctly diagnosed by CPUS, with a diagnostic accuracy of 92.3%, the PPV was 91.1%, NPV was 93.1%, the sensitivity was 89.1%, the specificity was 94.3%, the PLR was 16, and the NLR was 0.12. Comparison of CT and CPUS in the diagnosis of CPE, there was no statistically significant difference between the two methods ( X 2 = 0.111, P > 0.05). And The Cohen's kappa for the diagnosis of CPE by CT and CPUS is 0.873 (95% CI was 0.782–0.963, P < 0.001). Conclusions In conclusion, the present study suggests that CPUS is feasible for identifying cardiogenic pulmonary edema in ICU patients with heart failure. Based on diagnostic agreement analysis, CPUS demonstrates promising performance for CPE detection in this critically-ill cohort.
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Zhong et al. (2026) conducted an observational in Heart failure with suspected cardiogenic pulmonary edema (n=117). Cardiopulmonary ultrasound (CPUS) vs. Chest computed tomography (CT) was evaluated on Detection rate and diagnostic accuracy of cardiogenic pulmonary edema (Cohen's kappa 0.873, 95% CI 0.782-0.963, p=<0.001). Cardiopulmonary ultrasound demonstrated a diagnostic accuracy of 92.3% for cardiogenic pulmonary edema, showing no significant difference compared to chest CT and excellent diagnostic agreement.
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