Novel Therapeutic Strategies to Enhance Recovery after Myocardial Infarction: The Role of Biomarkers and Regenerative Medicine.

Recovery after myocardial infarction remains a major clinical challenge due to irreversible cardiomyocyte loss, adverse ventricular remodeling, myocardial fibrosis, and progression to chronic heart failure. Recent advances in cardiovascular medicine have shifted therapeutic strategies toward early identification of high-risk patients and promotion of myocardial repair through regenerative approaches. Novel cardiac biomarkers reflecting myocardial injury, inflammation, fibrosis, angiogenesis, and ventricular remodeling have improved risk stratification, prognosis assessment, and monitoring of therapeutic response. Regenerative medicine offers promising opportunities through stem cell-based therapies, extracellular vesicles, tissue engineering, biomaterial scaffolds, gene therapy, and biologically active molecules that stimulate myocardial regeneration and vascular repair. Integration of biomarker-guided monitoring with regenerative interventions may enhance myocardial recovery, preserve cardiac function, and reduce long-term cardiovascular complications. Personalized therapeutic strategies based on molecular profiling and regenerative potential are expected to improve patient selection and optimize clinical outcomes. The combination of advanced biomarkers and regenerative medicine represents an important direction in precision cardiology, offering new prospects for enhancing functional recovery and long-term prognosis after myocardial infarction. https://doi.org/10.52783/jchr.v16.i4.15655