Key result
Review outlines mechanisms, diagnostic hurdles, and management strategies for coexisting heart failure and embolism.
Why the study?
Heart failure and embolism frequently coexist with shared pathophysiologic mechanisms and present diagnostic challenges requiring appropriate imaging and management strategies.
Provides a comprehensive overview of the pathophysiological links, diagnostic challenges, and guideline-directed management strategies for the frequent coexistence of heart failure and embolism.
Heart failure and embolism frequently coexist and share common pathophysiologic mechanisms, including stasis, endothelial dysfunction and inflammation. Their clinical presentations can often be misleading, which makes the diagnostic challenging and mandates appropriate use of different imaging techniques. This article summarizes the pathophysiological links, diagnostic challenges and management strategies of these 2 entities. It also outlines evidence-based and guideline-directed strategies for prevention and treatment, including the role of inflammation, atrial cardiomyopathy and updated anticoagulation recommendations.
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Frost et al. (2026) conducted a review in Heart failure and embolism. This review summarizes the pathophysiological links, diagnostic challenges, and evidence-based management strategies for coexisting heart failure and embolism.
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