Key result
Among 10 patients with autosomal dominant polycystic kidney disease who experienced spontaneous coronary artery dissection, 80% were female, and no fatalities occurred during follow-up.
Why the study?
The relationship between spontaneous coronary artery dissection and autosomal dominant polycystic kidney disease remains poorly understood and has been scarcely reported.
Systematic Review (n=10)
We report an unusual case of spontaneous coronary artery dissection in a 59-year-old patient with autosomal dominant polycystic kidney disease who presented with mild intermittent chest discomfort during hiking. Coronary computed tomography angiography revealed an unexpected dissection flap in the left main coronary artery extending to the proximal part of the left anterior descending artery. After transcatheter placement of a coronary stent, the patient had no recurrent discomfort even during heavy exercise.
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Lee et al. (2010) conducted a systematic review in Spontaneous Coronary Artery Dissection (SCAD) and Autosomal Dominant Polycystic Kidney Disease (ADPKD) (n=10). Autosomal dominant polycystic kidney disease (ADPKD) was evaluated on Clinical characteristics, treatment, and outcomes of SCAD in ADPKD patients. Among 10 patients with autosomal dominant polycystic kidney disease who experienced spontaneous coronary artery dissection, 80% were female, and no fatalities occurred during follow-up.
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