Key result
Impaired heart rate turbulence and variability link to worse cardiac remodeling and function in hypertension.
Why the study?
The correlations between heart rate variability and turbulence parameters in patients with second-degree arterial hypertension were not well characterized.
Cross-Sectional (n=214)
Yes
Objective: to analyze the correlations of the parameters of heart rate variability (HRV) and heart rate turbulence (HRT) in patients with arterial hypertension of the II-nd degree. Material and methods. We have studied the parameters of heart rate variability and turbulence in 214 persons with arterial hypertension of the II-nd degree, of them 80.8 % having ventricular arrhythmias according to the Holter monitoring. We have analyzed the correlations of the parameters with the patient’s age, average heart rate (HR), circadian index (CI), left ventricular mass index (LVMI) and left ventricular ejection fraction (LVEF). The statistical analysis of the results has been made using the analytical package «Statistica» 10.0. Results. We have revealed statistically significant correlations of the HRV parameters with the age of patients, average HR, circadian index, ejection fraction. Thus, high level of the statistical significance of the interrelation of HRV parameters has been confirmed. We have received statistically significant correlations of the HRT parameters with the left ventricular mass index (LVMI), ejection fraction, HR average, quantity ventricular extrasystoles. High level of the statistical significance of the interrelation of HRT parameters (TO and TS) has been revealed. Conclusion. The received results can be used during the selection of the group of patients with arterial hypertension having high risk for unfavorable outcomes. Taking into account the features of the heart rate variability and turbulence parameters and factors associated with them this will enable the individualization of the assessment of the risk in arterial hypertension as much as possible and prescription of adequate treatment for each patient.
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Tetyana V. Aleynikova (2016) conducted a cross-sectional in Arterial hypertension II degree (n=214). Heart rate variability and turbulence parameters was evaluated on Correlation of heart rate variability and heart rate turbulence parameters with clinical and echocardiographic variables (age, HR, circadian index, LVMI, LVEF) (p=<0.05). Heart rate turbulence and variability parameters showed statistically significant correlations with age, average heart rate, left ventricular mass index, and ejection fraction in patients with stage II arterial hypertension.
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