Progressive Healing and Sustained Closure of an Infected Dehisced Knee Wound After Total Knee Arthroplasty During Use of a Silica-Based Fiber Matrix and Topical Cream

An 81-year-old woman developed a streptococcal postoperative wound infection after total knee arthroplasty (TKA).The anterior knee incision subsequently dehisced.Orthopedic surgery, infectious disease, and wound care clinicians managed the wound with systemic antibiotics, immobilization, and ongoing wound care.On postoperative Day 91, designated Treatment (Tx) Day 0, a twice-daily topical regimen using SiOxD Wound Matrix and SiOxC Cream was introduced as an adjunct to care: the matrix was applied when the injury site was wet, and the cream when the site was covered and dry.Serial photographs documented a persistent dark wound covering during the first month after product initiation, evolving wound-bed appearance at Tx Days 57-121, and progressive closure of the visible wound area through Tx Day 151.The photograph obtained on Tx Day 192 showed an apparently epithelialized scar.At the one-year follow-up after TKA, the treating physician confirmed wound closure, without reported recurrent ulceration or dehiscence.The patient reported no irritation, allergic reactions, maceration, application-related pain, bleeding, recurrent infection, or treatment discontinuations.This case describes sustained wound closure during multidisciplinary care that included adjunctive use of a silica-based matrix and topical cream; the contribution of either product cannot be determined from a single case.