Key result
Percutaneous coronary intervention in chronic coronary syndrome had a 2.0% (3/150) rate of in-hospital MACE, associated significantly only with the number of implanted stents.
Why the study?
Real-world data on in-hospital PCI outcomes for patients with chronic coronary syndrome in developing countries remain limited.
What are the in-hospital outcomes and predictors of major adverse cardiovascular events (MACE) following percutaneous coronary intervention in patients with chronic coronary syndrome?
Cohort (n=150)
No
What are the in-hospital outcomes and predictors of major adverse cardiovascular events (MACE) following percutaneous coronary intervention in patients with chronic coronary syndrome?
In a single-center Egyptian cohort of low-risk chronic coronary syndrome patients, PCI yielded a low incidence of in-hospital MACE (3 of 150 patients), with the number of implanted stents being the only factor significantly associated with events.
Background: Coronary artery disease (CAD) is the leading cause of cardiovascular mortality worldwide. Percutaneous coronary intervention (PCI) is an established revascularization strategy for chronic coronary syndrome (CCS), with outcomes influenced by patient and procedural factors. However, real-world data on in-hospital PCI outcomes from developing countries remain limited. Aim: To evaluate in-hospital outcomes of PCI in patients with CCS and assess the relationship between baseline clinical risk factors and in-hospital major adverse cardiovascular events (MACE). Patients and Methods: This prospective observational cohort study included 150 patients with CCS (mean age 58.9±8.5 years; 106 males and 44 females) who underwent coronary angiography and PCI. Results: Only three patients experienced in-hospital MACE. We found no significant associations between MACE and demographic characteristics, cardiovascular risk factors, ECG or echocardiographic findings, laboratory parameters, previous revascularization, or target vessel. The only statistically significant univariate association with in-hospital MACE was observed for the number of implanted stents. Overall, the cohort demonstrated a low-risk clinical and anatomical profile. Conclusion: PCI in patients with chronic coronary syndrome was associated with a high procedural success rate, low incidence of in-hospital MACE, and favorable short-term outcomes. We could not establish reliable associations with in-hospital MACE because of the very low number of events; however, the number of implanted stents showed a statistically significant univariate association with MACE.
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Elkader et al. (2026) conducted a cohort in Chronic coronary syndrome (symptomatic obstructive coronary artery disease) (n=150). Percutaneous coronary intervention (PCI) was evaluated on In-hospital major adverse cardiovascular events (MACE). Percutaneous coronary intervention in chronic coronary syndrome had a 2.0% (3/150) rate of in-hospital MACE, associated significantly only with the number of implanted stents.
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