Key result
Transradial PCI reduces major bleeding ~73% vs. transfemoral access with comparable procedural success.
Why the study?
Femoral access for PCI carries a notable risk of local hemorrhagic complications associated with increased morbidity and mortality in the era of potent antithrombotics. Simultaneously, interest in transradial PCI is growing as its indications expand to complex lesions, prompting discussion of its potential as a default route and associated concerns.
Supports transradial preference in primary PCI to cut bleeding; leaves open role in complex lesions despite device advances.
Advances in percutaneous coronary intervention (PCI) and peri-procedural potent antithrombotic treatments during the past decade have dramatically improved the outcomes of ischemic heart disease. The femoral artery is the vascular route used in PCI in most catheterization labs. However, when the femoral artery is used as the approaching vessel, local hemorrhagic complication is not rare in the era of potent antithrombotics. Recent studies have suggested that peri-procedural bleeding complications after PCI are associated with increased short- and long-term morbidity and mortality. On the other hand, there has been growing interest in transradial PCI due to rare complications at the puncture site, patient conveniences, early discharge and shortened hospitalization periods. Furthermore, the indications of transradial PCI are expanding to the complex lesion subsets due to the miniaturization of devices used, improvement of devices and techniques, and accumulated experience with the use of transradial PCI. In this review, we discuss the data of transradial PCI as a potential default route in coronary artery interventions, as well as other issues that may raise concerns with transradial PCI.
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Kim et al. (2011) conducted a review in Coronary artery disease undergoing percutaneous coronary intervention. Transradial coronary intervention (TRI) vs. Transfemoral coronary intervention (TFI) was evaluated. Transradial PCI achieves comparable procedural success to transfemoral PCI while reducing major bleeding by 73% and composite death, MI, or stroke in primary PCI (OR 0.56, 95% CI 0.39-0.79).
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