Why the study?
Patients with implantable cardioverter-defibrillators are often excluded from 3.0T cardiac MRI due to device-induced image artifacts, prompting the transfer and optimization of 1.5T sequence protocols for human application at 3.0T.
Does an optimized 3.0T CMR protocol using contrast-enhanced spoiled GRE CINE and wideband PSIR LGE (3 kHz bandwidth, +750 Hz offset) reduce ICD-induced image artifacts compared to conventional bSSFP CINE and conventional PSIR LGE in patients with implantable cardioverter-defibrillators?
Observational (n=15)
Does an optimized 3.0T CMR protocol using contrast-enhanced spoiled GRE CINE and wideband PSIR LGE (3 kHz bandwidth, +750 Hz offset) reduce ICD-induced image artifacts compared to conventional bSSFP CINE and conventional PSIR LGE in patients with implantable cardioverter-defibrillators?
Answers are grounded in this paper and cite their sources.
This study demonstrates the clinical feasibility of 3.0T cardiac MRI in patients with implanted ICDs by utilizing contrast-enhanced spoiled GRE for CINE and wideband PSIR (3 kHz bandwidth, +750 Hz offset) for LGE to substantially suppress device-induced artifacts.
Patients with implantable cardioverter-defibrillators (ICDs) often are excluded from receiving CMR scans at 3.0T due to ICD-induced image artifacts. This work aims to transfer sequence protocols established for CMR imaging in the presence of ICDs at 1.5T to a first human application at 3.0T. All measurements were performed on a clinical 3T MRI scanner. Phantom measurements were used to establish and optimize wideband PSIR LGE imaging at 3.0T. Volunteer measurements with externally placed ICDs were used for optimization of CINE imaging and wideband PSIR imaging. Thirdly, patients with implanted ICD were examined with the optimized protocols. Human measurements showed that SA stacks obtained with spoiled GRE after contrast agent showed a markedly lower artifact burden than the conventional approach. For scar imaging, a wideband PSIR with a bandwidth of 3kHz and a frequency offset of +750Hz allowed a sufficient suppression of relevant artifacts in the majority of scans. No strong correlation between the image quality and the distance between the cardiac silhouette and the device was detected. The presented work shows the feasibility of clinical cardiac MRI at 3.0T including GRE-CINE and wideband PSIR-LGE for patients with ICDs.
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Reiter et al. (2026) conducted an observational in Patients with implanted implantable cardioverter-defibrillators (ICDs) undergoing 3.0T cardiac MRI (n=15). 3.0T CMR protocol using contrast-enhanced spoiled GRE-CINE and wideband PSIR-LGE (bandwidth 3kHz, frequency offset +750Hz) vs. Conventional 3.0T CMR sequences (bSSFP CINE and conventional PSIR-LGE with 1000 Hz bandwidth) was evaluated on Artifact-free diagnostic evaluation of myocardial scar on LGE imaging (in the paired comparison subgroup of 7 patients).
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