Key result
Elderly age is linked to ~45% higher odds of increased depressive symptoms after elective PCI.
Why the study?
Depression is a common comorbidity in coronary artery disease and a risk factor for recurrent cardiac events and mortality, motivating this evaluation of the impact of elective PCI on depressive mood in elderly patients with chronic stable angina.
Observational (n=171)
No
Answers are grounded in this paper and cite their sources.
May warrant closer post-PCI depressive symptom monitoring in elderly patients; hypothesis-generating for prospective trials.
Background: Depression is a common comorbid condition in patients with coronary artery disease and a well-documented risk factor for recurrent cardiac events and mortality.We examined the impact of percutaneous coronary intervention (PCI) on depressive mood in elderly patients with chronic stable angina.Methods: Consecutive patients with chronic stable angina (n=171) who had undergone elective PCI from January 2010 to May 2010 were included in this study.Patients were divided into elderly (≥65 years) and non-elderly groups (<65 years) and then completed the 21-item Beck Depression Inventory I (BDI-I) at baseline and prior to discharge to assess for depressive symptoms.Results: Seventy-three (43%) patients were assigned to the elderly group and 98 (57%) to the non-elderly group.Using multivariate regression analysis, we found that the elderly group had a higher prevalence of joint, lung, and gastrointestinal diseases; were less religious and less likely to be employed; had lower rates of private health insurance; and were, less frequently, users of regular alcohol, current smokers, and regular exercisers compared to the non-elderly patients.The mean difference in BDI-I scores at baseline and pre-discharge was higher in elderly patients.Conclusion: Our study showed a correlation between the extent of depression and elective PCI, especially in elderly patients.This population should be assessed routinely for depressive symptoms and managed accordingly.
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Yoon et al. (2011) conducted an observational in Chronic stable angina pectoris (n=171). Elderly age (>=65 years) undergoing elective PCI vs. Non-elderly age (<65 years) undergoing elective PCI was evaluated on Mean difference in Beck Depression Inventory-I (BDI-I) score between admission and discharge (OR 1.447, 95% CI 1.079-2.687, p=0.040). Elderly age (>=65 years) was associated with a greater increase in BDI-I depressive symptom scores after elective PCI compared to younger patients (+1.22 vs +0.31; OR 1.447, 95% CI 1.079-2.687; p=0.04).
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