Ultrasound guided Pectoral Nerve Block II (PNB II) with Bupivacaine only versus PNB II with Bupivacaine and Dexmedetomidine for postoperative analgesia of modified radical mastectomy (Randomized controlled trial)

Breast cancer is one of the most common malignancies in women, which is often accompanied by negative emotions. Surgery is the primary treatment modality for breast cancer. However, pain after a radical mastectomy for breast cancer that is accompanied by breast loss can aggravate the negative emotions of patients. Ultrasound-guided Pecs II block has been widely used in women during breast cancer surgery. Combined with general anesthesia, it can reduce the dosage of opioids, relieve perioperative pain, and enhance the body’s immune function, which is conducive to the recovery of the patients., Aim and objectives; to compare the severity of the post-operative pain while using Pectoral nerve block II with Bupivacaine and Dexmedetomidine versus using Bupivacaine alone after modified radical mastectomy., Subjects and methods: This study was a randomized controlled trial that was performed in Al-Maadi Military Hospital, Surgery department over 46 Female patients who had modified radical mastectomy. Result; There was statistically significant difference between the studied cases as regard complications and there was statistically significant difference between the studied cases as regard VAS score immediate postoperative, after 9 hours and after 24 hours., Conclusion; Adding dexmedetomidine with bupivacaine in PECs 11 block decrease the requirements of analgesia and anesthesia drugs in modified radical mastectomy, also has less post operative complications.