Key result
Low-volume PCI centers without on-site CABG linked to ~2.4-fold higher in-hospital mortality.
Why the study?
PCI is performed in a wide range of institutions, motivating an assessment of the relationship between institutional CABG volume relative to PCI volume and clinical outcomes.
Cohort (n=220,934)
Yes
Answers are grounded in this paper and cite their sources.
Low-volume PCI without on-site CABG was associated with higher mortality; leaves open whether volume or surgical backup thresholds should guide referrals.
BACKGROUND: Percutaneous coronary intervention (PCI) is performed in a wide range of institutions. We sought to assess the relationship between coronary artery bypass grafting (CABG) volume relative to PCI volume and clinical outcome using nationally representative PCI and CABG registries in Japan. METHODS: This was a collaborative, registry-based cohort study enrolling patients undergoing percutaneous coronary intervention in 2013-2014 using Japanese nationwide registry (J-PCI) with follow up until discharge. The absolute volume of CABG for each hospital was calculated using additional data from Japan CardioVascular Surgery Database (JCVSD). Patients undergoing their first PCI registered in the registry (N = 220,934), at 943 facilities were studied. Main outcomes were in-hospital mortality, and incidence of composite of in-hospital death and postprocedural complications. RESULTS: Among the 220,934 patients, 162,411 were men, with a mean age of 69.7 (SD 11.6) years. Patients underwent PCI at hospitals with varying CABG volume: The overall in-hospital mortality and composite event rate for PCI patients was 0.9% and 2.4%, respectively. CABG volume was associated with the in-hospital mortality of PCI at facilities performing less than 200 PCIs per year, but not at facilities performing 200 or more. Similarly, in-hospital mortality or complication was associated with PCI volume <200 only if no CABG is done at the facility. The result remained largely consistent in subgroup of patients presenting with acute coronary syndrome or even after excluding these institutions with extremely low number of PCI (<50 cases/year) or CABG (<15 cases / year). CONCLUSIONS: In a nationwide registry-based analysis, the surgical volume was associated with patients' clinical outcome after PCI, when limited number of PCIs were performed at the facility.
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Kohsaka et al. (2020) conducted a cohort in Coronary artery disease undergoing percutaneous coronary intervention (n=220,934). Low institutional PCI volume (1-99/year) with no on-site CABG vs. High institutional PCI volume (≥400/year) and high CABG volume (≥50/year) was evaluated on In-hospital mortality (OR 2.38, 95% CI 1.56-3.63). Low-volume PCI facilities (<100/year) without on-site CABG had higher in-hospital mortality (OR 2.38, 95% CI 1.56-3.63) vs high-volume PCI (≥400/year) and CABG (≥50/year) centers.
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