Key result
Anticoagulation and heart failure therapy yield marked recovery in severe peripartum cardiomyopathy with multi-organ infarcts.
Why the study?
Peripartum cardiomyopathy is a rare cause of pregnancy-related strokes, and presentation with cerebral infarction accompanied by multi-organ ischemic damage is unusual.
Case Report (n=1)
No
This case highlights that peripartum cardiomyopathy can present late in the postpartum period with life-threatening multiterritorial stroke and multi-organ systemic thromboembolism, which can be successfully managed with early curative anticoagulation and guideline-directed heart failure therapy.
Answers are grounded in this paper and cite their sources.
May support anticoagulation and GDMT in peripartum cardiomyopathy with thromboembolism; hypothesis-generating pending prospective studies.
Peripartum cardiomyopathy is a rare cause of pregnancy-related strokes.We present a case of cerebral infarction with multi-organ ischemic damage complicating peripartum cardiomyopathy.A 25-year-old patient, with no cardiovascular risk factor, was admitted to Neurology at the University Hospital of Guadeloupe, for phasic disorders occurring eleven weeks postpartum of a pregnancy marked by gravidic hypertension.The assessments carried out revealed cerebral, splenic, renal infarctions and mesenteric thrombosis on cardiomyopathy with 25% LVEF and left intraventricular thrombus.Curative anticoagulation and treatment of heart failure were initiated on the first day of hospitalization, with a favorable outcome.A cardiological follow-up was organised, noting a progressive clinical improvement at a distance.Our case recalls the importance of a systematic medical follow-up in postpartum, and raises the possible gravity of the infarctions related to the CMPP, requiring an optimal care involving Cardiologists and Neurologists.
No takes yet. Share an insight, caveat, or question.
Mabila et al. (2023) conducted a case report in Peripartum cardiomyopathy complicated by multiterritorial cerebral infarction and multi-organ ischemic damage (n=1). Curative anticoagulation (heparin sodium followed by enoxaparin) and heart failure therapy (sacubitril/valsartan, spironolactone, furosemide, bisoprolol, dapagliflozin) was evaluated on Clinical neurological and left ventricular ejection fraction recovery. Curative anticoagulation and heart failure therapy in a 25-year-old with peripartum cardiomyopathy and multi-organ infarcts improved LVEF from 25% to 42% and NIHSS from 8 to 1.
Synapse has enriched 10 related papers. Consider them for comparative context: