经食道超声心动图检查在结构性心脏病中的临床应用价值

Q: What are the key findings of this study?

Transesophageal echocardiography achieved a higher overall diagnostic coincidence rate than transthoracic echocardiography in structural heart disease.

Q: What is the clinical evidence from this study?

Study design: Observational. Population: Structural heart disease (n=32). Intervention: Transesophageal echocardiography (TEE) vs. Transthoracic echocardiography (TTE). Primary outcome: Overall diagnostic coincidence rate compared against surgical findings, angiography, cardiac CT, or comprehensive clinical diagnosis (p=<0.05).

Q: What question did this study set out to answer?

To compare the diagnostic concordance rates of transesophageal echocardiography and transthoracic echocardiography across various structural heart conditions.

艳 肖

doi:10.37155/2717-5669-0706-23

January 1, 2026国际全科医学Open Access

经食道超声心动图检查在结构性心脏病中的临床应用价值

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Key result

TEE is linked to a ~38 percentage point higher diagnostic coincidence rate than TTE.

P<0.05
n=32

Why the study?

Does transesophageal echocardiography improve the diagnostic coincidence rate compared to transthoracic echocardiography in patients with structural heart disease?

Key Points

To compare the diagnostic concordance rates of transesophageal echocardiography and transthoracic echocardiography across various structural heart conditions.
Evaluated 32 patients with structural heart disease (18 males, 14 females; mean age 52.3 ± 11.6 years) between January 2026 and July 2027 using a Philips EPIQ7C color Doppler ultrasound system.
Performed transthoracic examinations with an S5-1 probe (1.3–4.2 MHz) and transesophageal examinations with an X7-2t probe (2.5–7.5 MHz) across multiple esophageal and transgastric views.
Calculated diagnostic concordance rates against surgical findings, cardiovascular angiography, cardiac CT, or comprehensive clinical diagnoses, analyzing differences using McNemar tests.
Transesophageal imaging achieved 100% concordance for atrial septal defects (12/12 vs. 66.7% [8/12], P < 0.05), left atrial appendage thrombi (8/8 vs. 37.5% [3/8], P < 0.01), prosthetic valve abnormalities (4/4 vs. 50.0% [2/4], P < 0.05), and cardiac masses (6/6 vs. 66.7% [4/6], P < 0.05).
Examinations were completed without severe complications such as esophageal perforation, hemorrhage, or cardiac arrhythmia.

Study Design

Type

Observational (n=32)

Blinding

Single-blind

Multicenter

No

Structured PICO

Does transesophageal echocardiography improve the diagnostic coincidence rate compared to transthoracic echocardiography in patients with structural heart disease?

P

Population

32 adult patients (mean age 52.3 years, 43.8% female) in China with structural heart disease including atrial septal defects, left atrial appendage thrombus, prosthetic valve dysfunction, or cardiac space-occupying lesions, free of esophageal contraindications.

I

Intervention

Transesophageal echocardiography (TEE) using a Philips EPIQ7C color Doppler ultrasound diagnostic system with an X7-2t transesophageal probe (frequency 2.5–7.5 MHz), performed after fasting for over 8 hours in the left lateral decubitus position via mid-esophageal, upper-esophageal, and transgastric multi-plane views.

C

Comparator

Transthoracic echocardiography (TTE) performed on the same patients using a Philips EPIQ7C system with an S5-1 cardiac probe (frequency 1.3–4.2 MHz) in the left lateral decubitus position via standard parasternal, apical, and subxiphoid views.

O

Outcome

Overall diagnostic coincidence rate (accuracy) defined as (true positive + true negative) / total cases × 100%, compared against a gold standard of surgical findings, cardiovascular angiography, cardiac CT, or comprehensive clinical diagnosis.surrogate

Main Result

Absolute Event Rate: 93.8% vs 56.3%

p-value: p=<0.05

Transesophageal echocardiography demonstrates a significantly higher diagnostic accuracy (93.8%) than transthoracic echocardiography (56.3%) for detecting atrial septal defects, left atrial appendage thrombi, prosthetic valve abnormalities, and intracardiac masses in structural heart disease.

Limitations

Limited field of view prevented comprehensive assessment in a case of atrial septal defect with complex intracardiac malformations
Acoustic shadowing from prosthetic valves obscured leaflet motion in one case of prosthetic valve dysfunction
Semi-invasive procedure carrying potential risks of esophageal perforation, bleeding, and arrhythmia
Small sample size (n=32) at a single center
Limited field of view in transesophageal echocardiography prevented comprehensive evaluation in 1 case of atrial septal defect combined with complex intracardiac malformation
Acoustic shadowing in transesophageal echocardiography obscured leaflet motion in 1 case of prosthetic valve dysfunction
Transesophageal echocardiography is a semi-invasive procedure with potential risks of esophageal perforation, bleeding, and arrhythmia

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Implication

May support TEE preference over TTE in structural heart disease; hypothesis-generating and requires prospective validation before practice change.

Abstract

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Discussion

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Cite This Study

艳肖 (2026) conducted an observational in Structural heart disease (n=32). Transesophageal echocardiography (TEE) vs. Transthoracic echocardiography (TTE) was evaluated on Overall diagnostic coincidence rate compared against surgical findings, angiography, cardiac CT, or comprehensive clinical diagnosis (p=<0.05). Transesophageal echocardiography achieved a higher overall diagnostic coincidence rate than transthoracic echocardiography in structural heart disease.

synapsesocial.com/papers/6af3386556c0fd1f7f33d935 https://doi.org/10.37155/2717-5669-0706-23

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经食道超声心动图检查在结构性心脏病中的临床应用价值

Key Points

Study Design

Structured PICO

Main Result

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

经食道超声心动图检查在结构性心脏病中的临床应用价值

Key Points

Study Design

Structured PICO

Main Result

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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