Key result
EnSite Contact Index-guided PulseSelect PVI linked to ~81% lower odds of residual high-voltage electrograms.
Why the study?
PulseSelect pulmonary vein isolation lacks a dedicated contact indicator, and electrical isolation alone does not confirm lesion transmurality.
Does EnSite Contact Index-guided catheter-tissue contact visualization improve procedural efficiency and reduce acute residual high-voltage unipolar electrograms in patients undergoing PulseSelect pulmonary vein isolation for atrial fibrillation?
Cohort (n=63)
No
Does EnSite Contact Index-guided catheter-tissue contact visualization improve procedural efficiency and reduce acute residual high-voltage unipolar electrograms in patients undergoing PulseSelect pulmonary vein isolation for atrial fibrillation?
Adapting the EnSite Contact Index module to the circular PulseSelect PFA catheter is clinically feasible and is associated with reduced fluoroscopy time and fewer acute residual high-voltage unipolar electrograms.
Answers are grounded in this paper and cite their sources.
Contact Index guidance may improve acute metrics in PulseSelect PVI; hypothesis-generating and should not yet change practice.
Background PulseSelect pulmonary vein isolation (PVI) lacks a dedicated contact indicator. Methods We retrospectively compared 63 patients undergoing PVI before and after EnSite Contact Index (CI) implementation. Because electrical isolation does not confirm lesion transmurality, post‐procedural unipolar electrograms (u‐EGMs) were assessed as acute surrogate markers. Results CI guidance was associated with more applications, shorter fluoroscopy, and in an exploratory analysis of analyzable patients, fewer residual high‐voltage u‐EGMs (1/20 vs. 8/24; p = 0.027). No complications occurred. Conclusions CI‐guided PVI was feasible; these procedural and acute electrophysiological associations require prospective validation.
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Mizobuchi et al. (2026) conducted a cohort in Atrial fibrillation undergoing pulmonary vein isolation (n=63). EnSite Contact Index (CI)-guided PulseSelect pulmonary vein isolation (threshold ≥25%) vs. Standard PulseSelect pulmonary vein isolation before Contact Index implementation was evaluated on Patients with residual high-voltage unipolar electrograms (>1.08 mV) on post-procedural mapping (analyzable subset, n=44) (OR 0.193, 95% CI 0.021-0.973, p=0.027). EnSite Contact Index guidance during PulseSelect PVI was associated with fewer residual high-voltage unipolar electrograms (5.0% vs 33.3%, p=0.027) and shorter fluoroscopy time (27 vs 37 min, p=0.001).
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