Cross-sectional study identifies distinct metabolic subtypes in individuals with cardiovascular-kidney-metabolic syndrome, suggesting early biomarker potential.
Key Points
Distinct metabolic subtypes associated with cardiovascular-kidney-metabolic syndrome were identified using metabolomic profiling.
A total of 390 metabolites were analyzed, leading to the discovery of three metabolic clusters with varying metabolic statuses.
High-risk individuals were predominantly classified into the cluster showing elevated metabolic status, indicating a strong correlation with CKM risk.
A panel of 20 metabolites demonstrated high diagnostic performance for stage 3 CKM, enhancing early detection efforts.