Table 2 from In Situ Proinflammatory Effects of Dazostinag Alone or with Chemotherapy on the Tumor Microenvironment of Patients with Head and Neck Squamous Cell Carcinoma

Richard C. Gregory; Neil Lineberry; Alexander Parent; Karthik Rajasekaran; Thomas J. Ow; Cherie‐Ann O. Nathan; Beryl A. Hatton; Wendy Jenkins; Marc Grenley; Connor Burns; Angela Merrell; Jason P. Frazier; Jonathan M.J. Derry; Emily Beirne; Richard A. Klinghoffer

doi:10.1158/2767-9764.29672719

July 30, 2025

Table 2 from In Situ Proinflammatory Effects of Dazostinag Alone or with Chemotherapy on the Tumor Microenvironment of Patients with Head and Neck Squamous Cell Carcinoma

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Key Points

MAIN FINDING: Dazostinag shows proinflammatory effects in the tumor microenvironment of head and neck cancer.
KEY EVIDENCE: Analysis includes detailed tumor and smoking data along with HPV status of individual patients.
APPROACH: The observational study evaluates the effects of dazostinag alone and in combination with chemotherapy.
SIGNIFICANCE: Understanding these effects may inform treatment strategies for head and neck squamous cell carcinoma patients.

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Implication

Observational analysis reveals proinflammatory effects of dazostinag on tumor microenvironment in patients with squamous cell carcinoma, suggesting implications for chemotherapy treatment.

Abstract

Tumor details and smoking and HPV status of individual patients

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Gregory et al. (2025) studied this question.

synapsesocial.com/papers/689a094be6551bb0af8cf409 https://doi.org/10.1158/2767-9764.29672719

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Table 2 from In Situ Proinflammatory Effects of Dazostinag Alone or with Chemotherapy on the Tumor Microenvironment of Patients with Head and Neck Squamous Cell Carcinoma

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

Table 2 from In Situ Proinflammatory Effects of Dazostinag Alone or with Chemotherapy on the Tumor Microenvironment of Patients with Head and Neck Squamous Cell Carcinoma

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

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