Figure 3 from In Situ Proinflammatory Effects of Dazostinag Alone or with Chemotherapy on the Tumor Microenvironment of Patients with Head and Neck Squamous Cell Carcinoma

The effect of dazostinag on macrophage polarization was further confirmed by IHC analysis. A, Treatment with dazostinag results in a more proinflammatory M1-like phenotype. B, Quantification of CD68⁺, CD163⁺, and CD86⁺ macrophages. The number of regions of interest analyzed for each patient and drug condition is detailed in Supplementary Table S4. CPPT, carboplatin; PTX, paclitaxel.