Table S1 from Body Mass Index, IGF1-Related Polymorphisms, and Risk of Familial Breast Cancer in Women with No BRCA1 or BRCA2 Pathogenic Variant

Barbara Fritsch-Humblet; Yue Jiao; Séverine Eon‐Marchais; Marie‐Gabrielle Dondon; Dorothée Le Gal; Juana Beauvallet; Dominique Stoppa‐Lyonnet; Nadine Andrieu; Fabienne Lesueur

doi:10.1158/1055-9965.29761960

August 1, 2025

Table S1 from Body Mass Index, IGF1-Related Polymorphisms, and Risk of Familial Breast Cancer in Women with No BRCA1 or BRCA2 Pathogenic Variant

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Key Points

MAIN FINDING: The study identifies specific SNPs associated with body mass index that may influence familial breast cancer risk.
KEY EVIDENCE: Selected SNPs were categorized by gene and biological pathways, highlighting their roles in cancer risk.
APPROACH: Analysis utilized SNP data to correlate body mass index with hereditary breast cancer risks in non-BRCA1 or BRCA2 women.
SIGNIFICANCE: Findings could improve understanding of genetic risk factors in familial breast cancer, aiding early detection strategies.

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Implication

Analysis of SNPs related to body mass index identifies genes linked to breast cancer risk in women without BRCA mutations, suggesting potential predictive factors.

Abstract

Table S1 provides the list of selected SNPs by gene and the biological pathways in which the genes are involved.

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Fritsch-Humblet et al. (2025) studied this question.

synapsesocial.com/papers/689a0c72e6551bb0af8d00f7 https://doi.org/10.1158/1055-9965.29761960

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Table S1 from Body Mass Index, IGF1-Related Polymorphisms, and Risk of Familial Breast Cancer in Women with No BRCA1 or BRCA2 Pathogenic Variant

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Table S1 from Body Mass Index, IGF1-Related Polymorphisms, and Risk of Familial Breast Cancer in Women with No BRCA1 or BRCA2 Pathogenic Variant

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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