Supplemental Table 1 from Breast Density Changes after Risk-Reducing Salpingo-oophorectomy in Women with a Pathogenic Germline Variant in BRCA1 or BRCA2

Elizabeth Loehrer; Frederieke H. van der Baan; Thea M. Mooij; Nadine Andrieu; Antonis C. Antoniou; Monique D. Dorrius; Douglas F. Easton; Christoph Engel; Karin Kast; Ritse M. Mann; Catherine Noguès; Rita K. Schmutzler; Yen Y. Tan; Mikael Eriksson; Carla H. van Gils; Maartje J. Hooning; Matti A. Rookus; Marjanka K. Schmidt

doi:10.1158/1055-9965.29760050

August 1, 2025

Supplemental Table 1 from Breast Density Changes after Risk-Reducing Salpingo-oophorectomy in Women with a Pathogenic Germline Variant in BRCA1 or BRCA2

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Key Points

Main finding shows changes in breast density after risk-reducing salpingo-oophorectomy in BRCA1 and BRCA2 carriers.
Key evidence includes descriptive statistics of 2356 BRCA carriers who had mammograms prior to surgery.
Approach involved analyzing mammogram data from participants in the IBCCS consortium for relevant findings.
Significance lies in understanding how surgery impacts breast density, which can inform future patient care and risk assessments.

Implication

Supplemental table reports breast density changes post-surgery in women with brca1 or brca2 variants, highlighting important health implications.

Abstract

Supplemental Table 1 includes the descriptive statistics of the 2356 BRCA1 or BRCA2 carriers in the IBCCS consortium who had any available mammograms prior to selection and inclusion in the current study

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Cite This Study

Loehrer et al. (2025) studied this question.

synapsesocial.com/papers/689a0c72e6551bb0af8d02fc https://doi.org/10.1158/1055-9965.29760050

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Supplemental Table 1 from Breast Density Changes after Risk-Reducing Salpingo-oophorectomy in Women with a Pathogenic Germline Variant in BRCA1 or BRCA2

Key Points

Implication

Abstract

Discussion

Cite This Study

Supplemental Table 1 from Breast Density Changes after Risk-Reducing Salpingo-oophorectomy in Women with a Pathogenic Germline Variant in BRCA1 or BRCA2

Key Points

Implication

Abstract

Discussion

Cite This Study

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