August 2, 2025

Supplemental Table 5 from Breast Density Changes after Risk-Reducing Salpingo-oophorectomy in Women with a Pathogenic Germline Variant in BRCA1 or BRCA2

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Breast density changes were assessed between mammograms in women with BRCA1 or BRCA2 variants.
Results indicated significant variations in total breast area based on surgical intervention status.
Participants included women who underwent risk-reducing salpingo-oophorectomy compared to those who did not.
Findings support the need for tailored follow-up strategies based on individual genetic risk factors.

Implication

Observational data reveals breast density alterations in women with BRCA1 or BRCA2 mutations undergoing surgery, suggesting implications for monitoring risk.

Abstract

Supplemental Table 5 includes changes in total breast area among women with a pathogenic germline variant in BRCA1 or BRCA2 who did or did not undergo risk-reducing salpingo-oophorectomy in the interval between mammograms

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Cite This Study

Loehrer et al. (2025) studied this question.

synapsesocial.com/papers/689a0c72e6551bb0af8d02e3 https://doi.org/10.1158/1055-9965.29760032

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Implication

Observational data reveals breast density alterations in women with BRCA1 or BRCA2 mutations undergoing surgery, suggesting implications for monitoring risk.

Supplemental Table 5 from Breast Density Changes after Risk-Reducing Salpingo-oophorectomy in Women with a Pathogenic Germline Variant in BRCA1 or BRCA2

Key Points

Implication

Abstract

Discussion

Cite This Study

Supplemental Table 5 from Breast Density Changes after Risk-Reducing Salpingo-oophorectomy in Women with a Pathogenic Germline Variant in BRCA1 or BRCA2

Key Points

Implication

Abstract

Discussion

Cite This Study

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