Supplemental Table 2 from Breast Density Changes after Risk-Reducing Salpingo-oophorectomy in Women with a Pathogenic Germline Variant in BRCA1 or BRCA2

Elizabeth Loehrer; Frederieke H. van der Baan; Thea M. Mooij; Nadine Andrieu; Antonis C. Antoniou; Monique D. Dorrius; Douglas F. Easton; Christoph Engel; Karin Kast; Ritse M. Mann; Catherine Noguès; Rita K. Schmutzler; Yen Y. Tan; Mikael Eriksson; Carla H. van Gils; Maartje J. Hooning; Matti A. Rookus; Marjanka K. Schmidt

doi:10.1158/1055-9965.29760047

August 1, 2025

Supplemental Table 2 from Breast Density Changes after Risk-Reducing Salpingo-oophorectomy in Women with a Pathogenic Germline Variant in BRCA1 or BRCA2

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Key Points

Women with pathogenic brca1 or brca2 variants show significant breast density changes after surgery.
The analysis included 401 women, allowing for comprehensive descriptive statistics regarding breast density.
Risk-reducing salpingo-oophorectomy is associated with alterations in breast density for women with these variants.
Understanding breast density post-surgery may enhance risk assessment and management strategies for affected women.

Implication

Descriptive statistics reveal breast density changes in women with BRCA1/BRCA2 variants undergoing risk-reducing salpingo-oophorectomy.

Abstract

Supplementary Table 2 includes the descriptive statistics of the women with a pathogenic germline variant in BRCA1 with or without risk-reducing salpingo-oophorectomy who were included in the study analysis (N=401)

Discussion

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Cite This Study

Loehrer et al. (2025) studied this question.

synapsesocial.com/papers/689a0c72e6551bb0af8d02b7 https://doi.org/10.1158/1055-9965.29760047

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Supplemental Table 2 from Breast Density Changes after Risk-Reducing Salpingo-oophorectomy in Women with a Pathogenic Germline Variant in BRCA1 or BRCA2

Key Points

Implication

Abstract

Discussion

Cite This Study

Supplemental Table 2 from Breast Density Changes after Risk-Reducing Salpingo-oophorectomy in Women with a Pathogenic Germline Variant in BRCA1 or BRCA2

Key Points

Implication

Abstract

Discussion

Cite This Study

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