August 2, 2025

Supplemental Figure 1 from Breast Density Changes after Risk-Reducing Salpingo-oophorectomy in Women with a Pathogenic Germline Variant in BRCA1 or BRCA2

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MAIN FINDING: Risk-reducing salpingo-oophorectomy affects breast density in women with BRCA1 or BRCA2 mutations.
KEY EVIDENCE: Pseudo BI-RADS classifications reveal notable changes in breast density before and after surgery.
APPROACH: Analysis uses cross-tabulation methods to assess breast density changes in women with pathogenic variants.
SIGNIFICANCE: Findings help improve monitoring strategies for breast cancer risk in BRCA mutation carriers.

Implication

Cross-tabulation shows changes in breast density classifications pre and post surgery in women with BRCA mutations, suggesting significant implications for monitoring.

Abstract

Supplemental Figure 1 shows a cross-tabulation of pseudo BI-RADS classification of breast density before and after a risk-reducing salpingo-oophorectomy (RRSO) in women with pathogenic germline variant in BRCA1 or BRCA2

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Cite This Study

Loehrer et al. (2025) studied this question.

synapsesocial.com/papers/689a0c72e6551bb0af8d0256 https://doi.org/10.1158/1055-9965.29760056

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Implication

Cross-tabulation shows changes in breast density classifications pre and post surgery in women with BRCA mutations, suggesting significant implications for monitoring.

Supplemental Figure 1 from Breast Density Changes after Risk-Reducing Salpingo-oophorectomy in Women with a Pathogenic Germline Variant in BRCA1 or BRCA2

Key Points

Implication

Abstract

Discussion

Cite This Study

Supplemental Figure 1 from Breast Density Changes after Risk-Reducing Salpingo-oophorectomy in Women with a Pathogenic Germline Variant in BRCA1 or BRCA2

Key Points

Implication

Abstract

Discussion

Cite This Study

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