August 2, 2025

Supplemental Table 6 from Breast Density Changes after Risk-Reducing Salpingo-oophorectomy in Women with a Pathogenic Germline Variant in BRCA1 or BRCA2

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Mammographic density changes were analyzed in women undergoing salpingo-oophorectomy compared to controls.
The study focused on women with pathogenic variants in BRCA1 or BRCA2 genes.
A sensitivity analysis was performed on mammograms taken with ≤2 years apart for accuracy.
Understanding breast density alterations can inform risk assessments for women with hereditary breast cancer syndromes.

Implication

Sensitivity analysis reveals mammographic density changes in women post-salpingo-oophorectomy, indicating potential risks.

Abstract

Supplemental Table 6 includes a sensitivity analysis to determine changes in mammographic density in women who underwent a risk-reducing salpingo-oophorectomy compared to women who did not undergo RRSO in the interval between mammograms, restricting to mammograms with ≤2 years between them

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Cite This Study

Loehrer et al. (2025) studied this question.

synapsesocial.com/papers/689a0c72e6551bb0af8d02f8 https://doi.org/10.1158/1055-9965.29760029

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Implication

Sensitivity analysis reveals mammographic density changes in women post-salpingo-oophorectomy, indicating potential risks.

Supplemental Table 6 from Breast Density Changes after Risk-Reducing Salpingo-oophorectomy in Women with a Pathogenic Germline Variant in BRCA1 or BRCA2

Key Points

Implication

Abstract

Discussion

Cite This Study

Supplemental Table 6 from Breast Density Changes after Risk-Reducing Salpingo-oophorectomy in Women with a Pathogenic Germline Variant in BRCA1 or BRCA2

Key Points

Implication

Abstract

Discussion

Cite This Study

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