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August 1, 2025

Table S5 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma

Tiankai Xie Josey C. Sorenson Logan G. Spector Nathan Pankratz R. Stephanie Huang Eiso Hiyama Jenny N. Poynter Gail E. Tomlinson Carolina Armengol Roland Kappler Michael E. Scheurer Eve Roman Aurora Castellano Michael A. Grotzer David S. Ziegler Saonli Basu Erin L. Marcotte Tianzhong Yang

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Key Points

MAIN FINDING: The study identifies candidate genes linked to hepatoblastoma across different ancestries.
KEY EVIDENCE: The METRO results include p-values and heritabilities, indicating genetic relevance in various populations.
APPROACH: The study utilizes a transcriptome-wide association approach with a focus on diverse ancestry data.
SIGNIFICANCE: These findings could advance the understanding of hepatoblastoma genetics, aiding in future research and therapies.

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Implication

Transcriptome-wide association study reveals candidate genes for hepatoblastoma across ancestries, implying genetic connections.

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Cite This Study

Xie et al. (2025) studied this question.

synapsesocial.com/papers/689a0c72e6551bb0af8d0132 https://doi.org/10.1158/1055-9965.29762020

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Synapse has enriched 8 closely related papers on similar clinical questions. Consider them for comparative context:

1Table S2 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025
2Table S6 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025
3Table S4 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025
4Figure S5 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025
5Figure S6 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025
6Figure S2 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025
7Figure S7 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025
8Table S3 from Multiancestry Transcriptome-Wide Association Study Identifies Candidate Genes Associated with Hepatoblastoma2025