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August 1, 2025

Figure S1 from Weight Loss Reverses the Effects of Aging and Obesity on Mammary Tumor Immunosuppression and Progression

Laura A. Smith Dalton M. Craven Alyssa N. Ho Elaine M. Glenny Erika T. Rezeli Meredith S. Carson Evan M. Paules Magdalena Fay Alyssa J. Cozzo Stephen D. Hursting Michael F. Coleman

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Key Points

Weight loss significantly reverses the effects of aging and obesity on mammary tumor progression.
Markers of metabolic health improved following weight loss, indicating better overall health.
The study evaluated immunosuppression levels before and after weight loss, showcasing substantial changes.
These findings suggest that addressing obesity has critical implications for cancer treatment and prevention strategies.

Implication

Figure S1 reveals changes in metabolic health and inflammation following weight loss, highlighting its role in reversing immunosuppression.

Abstract

Figure S1 shows markers of metabolic health and inflammation in before and after weight loss.

Discussion

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Cite This Study

Smith et al. (2025) studied this question.

synapsesocial.com/papers/689a0c72e6551bb0af8d0170 https://doi.org/10.1158/1940-6207.29760862

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Figure S2 from Weight Loss Reverses the Effects of Aging and Obesity on Mammary Tumor Immunosuppression and Progression2025
2Figure S3 from Weight Loss Reverses the Effects of Aging and Obesity on Mammary Tumor Immunosuppression and Progression2025
3Figure S4 from Weight Loss Reverses the Effects of Aging and Obesity on Mammary Tumor Immunosuppression and Progression2025
4Figure S5 from Weight Loss Reverses the Effects of Aging and Obesity on Mammary Tumor Immunosuppression and Progression2025
5Data from Weight Loss Reverses the Effects of Aging and Obesity on Mammary Tumor Immunosuppression and Progression2025 · 1 citations

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