August 2, 2025

Supplementary Fig.S18 from Comprehensive Characterization of Somatic Mutation Timing Reveals the Evolutionary Trajectory of Lung Adenocarcinoma in Chinese Patients

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MAIN FINDING: Frequent somatic mutations in coding driver genes correlate with noncoding driver elements.
KEY EVIDENCE: The analysis of mutation timing offers insights into the evolutionary trajectory of lung adenocarcinoma.
APPROACH: Comprehensive characterization was performed on somatic mutations in Chinese patients with lung adenocarcinoma.
SIGNIFICANCE: Understanding mutation patterns can help refine strategies for lung cancer treatment and prevention.

Implication

Analysis reveals the relationship between coding and noncoding driver mutations in lung adenocarcinoma, suggesting insights into cancer evolution.

The association between frequent mutations in coding driver genes and noncoding driver elements.

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Qin et al. (2025) studied this question.

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Analysis reveals the relationship between coding and noncoding driver mutations in lung adenocarcinoma, suggesting insights into cancer evolution.

The association between frequent mutations in coding driver genes and noncoding driver elements.