Table S2 from RGN6024 Is a Brain-Penetrant, Small-Molecule Tubulin Destabilizer for the Treatment of Glioblastoma

Key Points

• MAIN FINDING: RGN6024 effectively impacts the viability of glioblastoma cell lines, indicating its therapeutic potential.
• KEY EVIDENCE: The small-molecule shows significant effects on cell survival in various glioblastoma models.
• APPROACH: The research evaluated RGN6024's efficacy on glioblastoma cell lines to assess its treatment applicability.
• SIGNIFICANCE: This work highlights a promising brain-penetrant option in tackling glioblastoma, a challenging cancer.