August 2, 2025

Supplementary Fig.S20 from Comprehensive Characterization of Somatic Mutation Timing Reveals the Evolutionary Trajectory of Lung Adenocarcinoma in Chinese Patients

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The core finding highlights the relationship between early and late clonal mutations in lung adenocarcinoma.
Data on fold changes presents clear insights into the evolution of specific mutational signature types.
The analysis involved Chinese patients, providing important context for the study of lung adenocarcinoma.
Understanding mutation timing can help identify evolutionary trajectories that may influence treatment strategies.

Implication

Comprehensive analysis reveals shifts in clonal mutations in lung adenocarcinoma patients, suggesting genetic evolution patterns.

Fold changes between relative proportions of early and late clonal mutations attributed to specific combined mutational signature types.

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Qin et al. (2025) studied this question.

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Comprehensive analysis reveals shifts in clonal mutations in lung adenocarcinoma patients, suggesting genetic evolution patterns.

Fold changes between relative proportions of early and late clonal mutations attributed to specific combined mutational signature types.