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August 1, 2025

Table S1 from Combining Multiplexed CRISPR/Cas9-Nickase and PARP Inhibitors Efficiently and Precisely Targets Cancer Cells

Soyoung Lee Kyunghwan Kim Hye‐Jin Jeong Subin Choi Himchan Cheng Dayoung Kim Soomin Heo Jinhee Mun Minjong Kim Eunjin Lee Yoon Ji Choi Seon‐gyeong Lee Eun A Lee Yewon Jang Kayeong Lim Heon Seok Kim Euihwan Jeong Seung‐Jae Myung Deok‐Beom Jung Chang Sik Yu In Ho Song M. Ryan Corces Joo H. Kang Kyungjae Myung Taejoon Kwon Tae‐Eun Park Jinmyoung Joo Seung Woo Cho

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Key Points

Combining CRISPR/Cas9-nickase with PARP inhibitors effectively targets cancer cells in laboratory settings.
The study includes sequences of oligonucleotides utilized to achieve targeted therapy.
This approach leverages gene editing to enhance the treatment efficacy against cancerous cells.
The findings may lead to improved strategies for cancer therapy, advancing precision medicine efforts.

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Implication

Combining CRISPR/Cas9-nickase with PARP inhibitors efficiently targets cancer cells, highlighting a potential therapeutic approach.

Abstract

Table S1 shows the sequences of oligonucleotides used in this study.

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Cite This Study

Lee et al. (2025) studied this question.

synapsesocial.com/papers/689a0c72e6551bb0af8d021d https://doi.org/10.1158/0008-5472.29760152

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Table S3 from Combining Multiplexed CRISPR/Cas9-Nickase and PARP Inhibitors Efficiently and Precisely Targets Cancer Cells2025
2Figure S4 from Combining Multiplexed CRISPR/Cas9-Nickase and PARP Inhibitors Efficiently and Precisely Targets Cancer Cells2025
3Figure S12 from Combining Multiplexed CRISPR/Cas9-Nickase and PARP Inhibitors Efficiently and Precisely Targets Cancer Cells2025
4Table S2 from Combining Multiplexed CRISPR/Cas9-Nickase and PARP Inhibitors Efficiently and Precisely Targets Cancer Cells2025
5Table S4 from Combining Multiplexed CRISPR/Cas9-Nickase and PARP Inhibitors Efficiently and Precisely Targets Cancer Cells2025