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August 1, 2025

Supplementary figure S7 from Tumor Cell–Intrinsic Decr2 Regulates Ferroptosis and Immunotherapy Efficacy

Shuyin Li Jason W. Shapiro Hardik Shah Emily F. Higgs Lishi Xie Yaopeng Li Yuanyuan Zha Jonathan Trujillo Alexandra Cabanov Tyler A. Jones Blake Flood Ken Hatogai Ruxandra Tonea Justin Kline Thomas F. Gajewski

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Key Points

MAIN FINDING: Decr2 is found to influence ferroptosis and enhance immunotherapy efficacy in tumors.
KEY EVIDENCE: Analysis of the tumor microenvironment illustrates significant connections with decr2 activity.
APPROACH: The study involved detailed examination of supplementary microenvironment data related to tumors.
SIGNIFICANCE: Understanding decr2's role may improve therapeutic strategies for cancer treatments.

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Implication

Analysis reveals decr2 regulating ferroptosis and immunotherapy efficacy in tumor microenvironment, suggesting key interactions.

Abstract

Supplementary Figure S7. Tumor microenvironment analysis.

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Cite This Study

Li et al. (2025) studied this question.

synapsesocial.com/papers/689a0c72e6551bb0af8d0270 https://doi.org/10.1158/2326-6066.29760076

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary figure S4 from Tumor Cell–Intrinsic <i>Decr2</i> Regulates Ferroptosis and Immunotherapy Efficacy2025
2Supplementary figure S11 from Tumor Cell–Intrinsic <i>Decr2</i> Regulates Ferroptosis and Immunotherapy Efficacy2025
3Supplementary figure S9 from Tumor Cell–Intrinsic <i>Decr2</i> Regulates Ferroptosis and Immunotherapy Efficacy2025
4Supplementary figure S3 from Tumor Cell–Intrinsic <i>Decr2</i> Regulates Ferroptosis and Immunotherapy Efficacy2025
5Supplementary figure S10 from Tumor Cell–Intrinsic <i>Decr2</i> Regulates Ferroptosis and Immunotherapy Efficacy2025

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Supplementary figure S13 from Tumor Cell–Intrinsic <i>Decr2</i> Regulates Ferroptosis and Immunotherapy Efficacy2025