Figure S9 from Development and Application of Radioactive Ligands Targeting Fibroblasts with Albumin-Binding Sites

Tongtong Wu; Zhicong Yang; Sufan Tang; Hongmei Yuan; Yang Liu; Haiyang Li; Nan Liu; Zhanwen Huang; Yue Chen; Zhijun Zhou

doi:10.1158/1535-7163.29759923

August 1, 2025

Figure S9 from Development and Application of Radioactive Ligands Targeting Fibroblasts with Albumin-Binding Sites

View at Publisher

Ask AI

Bookmark

Share

Key Points

68Ga-labeled compounds show stabilities in saline and serum after 2 hours at 37 °C.
177Lu-labeled ligands maintain stabilities in saline and serum for 24 hours at 37 °C.
Radio-HPLC analysis is used to evaluate the stability of the compounds over time.
The findings support further development of radioactive ligands for targeting fibroblasts effectively.

Implication

Radio-HPLC shows stability of 68Ga and 177Lu-labeled ligands in serum, indicating potential for fibroblast targeting.

Abstract

Figure S9. (A) Radio-HPLC analysis of 68Ga-labeled compounds’ stabilities in saline and serum for 2 h at 37 °C. (B) Radio-HPLC analysis of 177Lu-labeled ligands’ stabilities in saline and serum for 24 h at 37 °C.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Wu et al. (2025) studied this question.

synapsesocial.com/papers/689a0c72e6551bb0af8d02c8 https://doi.org/10.1158/1535-7163.29759923

View at Publisher

Ask AI

Bookmark

Share

Figure S9 from Development and Application of Radioactive Ligands Targeting Fibroblasts with Albumin-Binding Sites

Key Points

Implication

Abstract

Discussion

Cite This Study

Figure S9 from Development and Application of Radioactive Ligands Targeting Fibroblasts with Albumin-Binding Sites

Key Points

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading