August 3, 2025Open Access
Comparative Effectiveness of CRT-P vs CRT-D in Octogenarians With HFrEF and LBBB: A Real-World, Propensity-Matched Cohort Study
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Overview
This cohort study evaluates 3-year mortality and hospitalization in octogenarians with HFrEF, suggesting CRT-D may reduce hospital visits without improving survival.
Key Points
- Three-year mortality rates were similar between CRT-D and CRT-P in octogenarians (37.2% vs 39.1%).
- CRT-D recipients had significantly fewer hospitalizations compared to CRT-P recipients (mean 4.05 vs 5.36; p = 0.032).
- Subgroup analysis revealed modestly lower mortality for CRT-D in patients with EF ≤25% and 26-35%, though not statistically significant.
- Female patients receiving CRT-D exhibited lower mortality rates than their male counterparts (20.0% vs 29.5%; HR 0.637).
Cite This Study
Ibe et al. (2025) studied this question.