⌘+K

Pulse Explore Clubs Researchers Journals

Home Clubs Explore

August 4, 2025

Table S1 from VAV2 Drives EGFR-Mediated Rac1 Responses in Prostate Cancer

Martin J. Baker Suli Zhang Daniel Zhang Joshua Searle Priti Lal Cornelis P. Vlaar Suranganie Dharmawardhane Martı́n C. Abba Marcelo G. Kazanietz Mariana Cooke

View Full Paper

Ask AI

Bookmark

Share

Key Points

MAIN FINDING: VAV2 plays a crucial role in mediating EGFR-driven Rac1 responses in prostate cancer cells.
KEY EVIDENCE: Analysis of differentially expressed genes revealed significant changes in Rac1 knockout DU145 cells.
APPROACH: The study utilized gene expression analysis to compare Rac1 KO cells with wild-type counterparts.
SIGNIFICANCE: Understanding VAV2 and Rac1 interactions may open new avenues for targeted therapies in prostate cancer.

No abstract yet

We only have this paper's title and publication details.

Read it at the source→

Implication

Experimental findings reveal disrupted gene expression in Rac1 KO DU145 cells, suggesting key pathways in prostate cancer progression.

Abstract

Table S1. Differentially expressed genes in Rac1 KO DU145 cells.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Baker et al. (2025) studied this question.

synapsesocial.com/papers/689a0f86e6551bb0af8d0996 https://doi.org/10.1158/1541-7786.29819515

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Table S4 from VAV2 Drives EGFR-Mediated Rac1 Responses in Prostate Cancer2025
2Supplementary Figure S7 from VAV2 Drives EGFR-Mediated Rac1 Responses in Prostate Cancer2025
3Supplementary Figure S4 from VAV2 Drives EGFR-Mediated Rac1 Responses in Prostate Cancer2025
4Supplementary Figure S1 from VAV2 Drives EGFR-Mediated Rac1 Responses in Prostate Cancer2025
5Supplementary Figure S6 from VAV2 Drives EGFR-Mediated Rac1 Responses in Prostate Cancer2025