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August 4, 2025Consilium MedicumOpen Access

Immunological aspects of polycystic ovary syndrome: A review

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Authors

YKYu.A. KandrashkinaЕОЕ. А. ОрловаASA. F. Shtakh

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Overview

This review explores how the immune system impacts infertility in women with polycystic ovary syndrome, suggesting chronic inflammation plays a key role.

Key Points

  • PCOS is linked to chronic inflammation, impairing oocyte development and contributing to infertility.
  • Elevated levels of interleukins indicate immune dysregulation associated with PCOS and its complications.
  • Research shows cytokine imbalance in PCOS could lead to negative outcomes in in vitro fertilization.
  • Understanding the immune mechanisms in PCOS may enhance diagnosis and treatment strategies.

Cite This Study

Kandrashkina et al. (2025) studied this question.

synapsesocial.com/papers/689a0f93e6551bb0af8d0ff0https://doi.org/10.26442/20751753.2025.7.203262
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Interconnection between Polycystic Ovary Syndrome, Immune Disorders, and Reproductive Outcomes2026 · 1 citations
  2. 2The role of immunity in insulin resistance in patients with polycystic ovary syndrome2025 · 11 citations
  3. 3Single-cell analysis of follicular fluid reveals dysregulation of ovulatory immune function in PCOS patients undergoing ovarian stimulation2026
  4. 4Single-cell analysis of follicular fluid reveals dysregulation of ovulatory immune function in PCOS patients undergoing ovarian stimulation2025 · 1 citations
  5. 5Disturbed Follicular Microenvironment in Polycystic Ovary Syndrome: Relationship to Oocyte Quality and Infertility2024 · 66 citations