Key result
PCOS is linked to chronic low-grade inflammation, especially alongside obesity, insulin resistance, and hyperandrogenism.
Why the study?
Inflammation has been implicated in the metabolic disturbances and menstrual irregularities of PCOS, but the role of cytokines and potential anti-inflammatory treatments requires clarification.
Population
Women of reproductive age with polycystic ovarian syndrome
Design
Review
Authors
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Supports inflammation as a PCOS feature in obesity/IR; leaves open anti-inflammatory interventions pending RCTs.
PCOS is characterized by a chronic low-grade inflammatory state, suggesting that targeting inflammation with anti-inflammatory agents could be a potential therapeutic strategy.
Ebejer et al. (2013) conducted a review in Polycystic ovarian syndrome (PCOS). Inflammation and cytokines was evaluated. Chronic low-grade inflammation, characterized by various inflammatory proteins, is present in women with PCOS, especially in cases of obesity, insulin resistance, and hyperandrogenism.
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