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August 4, 2025

Supplementary Figure 4 from Intrahepatic Microbial Heterogeneity in Multifocal Hepatocellular Carcinoma and Its Association with Host Genomic and Transcriptomic Alterations

Yinghong Lu Lixia Xu Weikang Chen Weixin Liu Ying Zhang Qianying Zhou Na Wang Yongxin Zhang Haojie Bai Shu Xu Pingmei Huang Kaili Fu Wenxuan Xie Xin Liu Xueliang Wang Chi Chun Wong Ming Kuang Jun Yu

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Key Points

Core finding shows significant intrahepatic microbial heterogeneity in patients with multifocal hepatocellular carcinoma (HCC).
High-variable microbes (HVMs) were identified, indicating their potential role in the disease process.
The research involved microbial profiling alongside genomic and transcriptomic analysis of the host.
Understanding these associations could inform future therapeutic strategies for managing multifocal HCC.

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Implication

Profiling high-variable microbes reveals associations with host genomic and transcriptomic alterations in multifocal HCC.

Abstract

Profiling of high-variable microbes (HVMs) in multifocal HCC patients

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Cite This Study

Lu et al. (2025) studied this question.

synapsesocial.com/papers/689a0f93e6551bb0af8d10e3 https://doi.org/10.1158/2159-8290.29819820

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure 1 from Intrahepatic Microbial Heterogeneity in Multifocal Hepatocellular Carcinoma and Its Association with Host Genomic and Transcriptomic Alterations2025
2Supplementary Figure 3 from Intrahepatic Microbial Heterogeneity in Multifocal Hepatocellular Carcinoma and Its Association with Host Genomic and Transcriptomic Alterations2025
3Supplementary Figure 5 from Intrahepatic Microbial Heterogeneity in Multifocal Hepatocellular Carcinoma and Its Association with Host Genomic and Transcriptomic Alterations2025
4Supplementary Figure 11 from Intrahepatic Microbial Heterogeneity in Multifocal Hepatocellular Carcinoma and Its Association with Host Genomic and Transcriptomic Alterations2025
5Supplementary Figure 9 from Intrahepatic Microbial Heterogeneity in Multifocal Hepatocellular Carcinoma and Its Association with Host Genomic and Transcriptomic Alterations2025