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August 4, 2025

Supplementary Figure 10 from Intrahepatic Microbial Heterogeneity in Multifocal Hepatocellular Carcinoma and Its Association with Host Genomic and Transcriptomic Alterations

Yinghong Lu Lixia Xu Weikang Chen Weixin Liu Ying Zhang Qianying Zhou Na Wang Yongxin Zhang Haojie Bai Shu Xu Pingmei Huang Kaili Fu Wenxuan Xie Xin Liu Xueliang Wang Chi Chun Wong Ming Kuang Jun Yu

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Key Points

MAIN FINDING: Microbial heterogeneity exists between tumor and stool samples in patients with hepatocellular carcinoma.
KEY EVIDENCE: Differences are observed in both multicentric and single-lesion HCC tissue samples regarding microbial composition.
APPROACH: Tissue samples were compared to stool to analyze microbial abundance and composition in HCC patients.
SIGNIFICANCE: Understanding microbial differences may highlight connections with genomic and transcriptomic alterations in liver cancer.

Implication

Analysis shows microbial differences in HCC tissues compared to stool samples, implying links to genomic and transcriptomic changes.

Abstract

Microbial composition and abundance between stool and HCC tumor tissues, single-lesion and multi-lesion HCC samples from HCC patients

Discussion

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Cite This Study

Lu et al. (2025) studied this question.

synapsesocial.com/papers/689a0f93e6551bb0af8d10e6 https://doi.org/10.1158/2159-8290.29819835

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure 1 from Intrahepatic Microbial Heterogeneity in Multifocal Hepatocellular Carcinoma and Its Association with Host Genomic and Transcriptomic Alterations2025
2Supplementary Figure 11 from Intrahepatic Microbial Heterogeneity in Multifocal Hepatocellular Carcinoma and Its Association with Host Genomic and Transcriptomic Alterations2025
3Supplementary Figure 3 from Intrahepatic Microbial Heterogeneity in Multifocal Hepatocellular Carcinoma and Its Association with Host Genomic and Transcriptomic Alterations2025
4Supplementary Figure 9 from Intrahepatic Microbial Heterogeneity in Multifocal Hepatocellular Carcinoma and Its Association with Host Genomic and Transcriptomic Alterations2025
5Supplementary Figure 4 from Intrahepatic Microbial Heterogeneity in Multifocal Hepatocellular Carcinoma and Its Association with Host Genomic and Transcriptomic Alterations2025