⌘+K

Pulse Explore Clubs Researchers Journals

Home Clubs Explore

August 4, 2025

Figure S5 from Targeted Deletion of Cxcl1 in MSCs Regulates Osteogenesis and Suppresses Bone-Metastatic Prostate Cancer

Catherine S. Johnson Diane L. Costanzo-Garvey Julio C. Valencia Sanjana Rajgopal Theodore Reed Emma R. Brannon Jeremy S. Frieling Deanna D. Mosley Todd A. Wyatt Elijah F. Edmondson Kabhilan Mohan Grinu Mathew Leah M. Cook

View Full Paper

Ask AI

Bookmark

Share

Key Points

Main finding: Deletion of cxcl1 in mses regulates osteogenesis and impacts prostate cancer growth.
Key evidence: Cxcl1 knockout mses effectively reduce rm1 cancer cell proliferation.
Approach: The study used targeted deletion techniques in mouse models to observe changes in osteogenesis.
Significance: This research highlights the potential for cxcl1 targeting in treatments for bone-metastatic prostate cancer.

No abstract yet

We only have this paper's title and publication details.

Read it at the source→

Implication

Targeted deletion of cxcl1 in mses suppresses proliferation in prostate cancer, indicating a role in bone health.

Abstract

Cxcl1 KO MSCs suppress RM1 proliferation

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Johnson et al. (2025) studied this question.

synapsesocial.com/papers/689a0f93e6551bb0af8d10ed https://doi.org/10.1158/1541-7786.29819724

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Figure S7 from Targeted Deletion of Cxcl1 in MSCs Regulates Osteogenesis and Suppresses Bone-Metastatic Prostate Cancer2025
2Figure S1 from Targeted Deletion of Cxcl1 in MSCs Regulates Osteogenesis and Suppresses Bone-Metastatic Prostate Cancer2025
3Figure S2 from Targeted Deletion of Cxcl1 in MSCs Regulates Osteogenesis and Suppresses Bone-Metastatic Prostate Cancer2025
4Figure S3 from Targeted Deletion of Cxcl1 in MSCs Regulates Osteogenesis and Suppresses Bone-Metastatic Prostate Cancer2025
5Table S1 from Targeted Deletion of Cxcl1 in MSCs Regulates Osteogenesis and Suppresses Bone-Metastatic Prostate Cancer2025