⌘+K

Pulse Explore Clubs Researchers Journals

Home Clubs Explore

August 4, 2025

Figure S1 from Targeted Deletion of Cxcl1 in MSCs Regulates Osteogenesis and Suppresses Bone-Metastatic Prostate Cancer

Catherine S. Johnson Diane L. Costanzo-Garvey Julio C. Valencia Sanjana Rajgopal Theodore Reed Emma R. Brannon Jeremy S. Frieling Deanna D. Mosley Todd A. Wyatt Elijah F. Edmondson Kabhilan Mohan Grinu Mathew Leah M. Cook

View Full Paper

Ask AI

Bookmark

Share

Key Points

Targeted deletion of cxcl1 in mesenchymal stem cells (MSCs) enhances osteoblast differentiation.
CXCL1/8 knockdown significantly alters osteogenesis in bone cells.
The study utilized a targeted deletion approach to assess changes in MSC function.
Findings may provide insights into therapies for bone-related diseases and prostate cancer treatment.

No abstract yet

We only have this paper's title and publication details.

Read it at the source→

Implication

Targeted deletion increases osteoblast differentiation in MSCs, suggesting a role in regulating bone health and cancer progression.

Abstract

CXCL1/8 KD Increases MSC Osteoblast Differentiation

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Johnson et al. (2025) studied this question.

synapsesocial.com/papers/689a0f93e6551bb0af8d10f5 https://doi.org/10.1158/1541-7786.29819736

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Figure S7 from Targeted Deletion of Cxcl1 in MSCs Regulates Osteogenesis and Suppresses Bone-Metastatic Prostate Cancer2025
2Figure S5 from Targeted Deletion of Cxcl1 in MSCs Regulates Osteogenesis and Suppresses Bone-Metastatic Prostate Cancer2025
3Figure S2 from Targeted Deletion of Cxcl1 in MSCs Regulates Osteogenesis and Suppresses Bone-Metastatic Prostate Cancer2025
4Figure S3 from Targeted Deletion of Cxcl1 in MSCs Regulates Osteogenesis and Suppresses Bone-Metastatic Prostate Cancer2025
5Table S1 from Targeted Deletion of Cxcl1 in MSCs Regulates Osteogenesis and Suppresses Bone-Metastatic Prostate Cancer2025