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August 5, 2025Catheterization and Cardiovascular Interventions

Inflammatory Markers and Contrast‐Induced Nephropathy Risk: A Meta‐Analysis of NLR and PLR in ACS Patients Undergoing Percutaneous Coronary Intervention

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Authors

HAHashim M. AlHammouriOMOsama M. MustafaNMNour Mash’al

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Overview

Meta-analysis reveals NLR and PLR predictive potential for CIN risk in ACS patients, suggesting monitoring could enhance patient outcomes.

Key Points

  • Preprocedural NLR and PLR are linked to increased CIN risk in ACS patients undergoing PCI.
  • Elevated NLR showed a pooled odds ratio of 1.21, indicating a significant association with CIN.
  • NSTEMI patients demonstrated a stronger association with a pooled odds ratio of 2.03, highlighting the importance of NLR and PLR.
  • NLR and PLR are accessible biomarkers that may improve early identification of high-risk patients for targeted strategies.

Cite This Study

AlHammouri et al. (2025) studied this question.

synapsesocial.com/papers/689a0f93e6551bb0af8d1228https://doi.org/10.1002/ccd.70056
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Platelet-to-Lymphocyte Ratio Predicts Contrast-Induced Nephropathy in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome2015 · 44 citations
  2. 2Association of Neutrophil-to-Lymphocyte Ratio With Clinical Outcomes After Percutaneous Coronary Intervention2025 · 6 citations
  3. 3Association Between Inflammatory Biomarkers and Contrast-induced Acute Kidney Injury in ACS Patients Undergoing Percutaneous Coronary Intervention: A Cross-sectional Study2023 · 30 citations
  4. 4Neutrophil–Lymphocyte Ratio and Platelet–Lymphocyte Ratio Combination Can Predict Prognosis in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention2014 · 100 citations
  5. 5Association of Neutrophil‐to‐Lymphocyte and Platelet‐to‐Lymphocyte Ratios With Three‐Vessel Coronary Artery Disease: A Case‐Control Study2026