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August 16, 2025

Bacteria-Targeted Single-Atom Nanozyme With Photothermal-Augmented Multi-Enzymatic Cascade and NO Delivery for Enhanced Infected Wound Healing.

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Authors

JCJunyang ChenQCQing ChenXQXudong Qin

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Overview

Multifunctional nanoplatform improved antibacterial efficacy and promoted angiogenesis in infected wounds, suggesting a new strategy for diabetic healing.

Key Points

  • CBPV demonstrates 99.6% inactivation of methicillin-resistant Staphylococcus aureus, enhancing wound healing.
  • In vitro and in vivo studies reveal CBPV's significant antibacterial efficacy and improved wound healing metrics.
  • Assessment using a multifunctional nanoplatform integrates bacteria-targeting, NO delivery, and photothermal therapy.
  • Highlights potential advancements in managing complex diabetic wounds through targeted therapeutic approaches.

Cite This Study

Chen et al. (2025) studied this question.

synapsesocial.com/papers/68a368840a429f797332da83https://doi.org/10.1002/advs.202509621
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  5. 5A Self-Oxygenating Nanozyme Cascade System for Drug-Resistant Bacterial Infected Diabetic Wound Healing2025