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August 17, 2025Frontiers in NeurologyOpen Access

Comparing burden of ischemic stroke caused by high low-density lipoprotein cholesterol in global and China: trends and projections

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Authors

JZJiali ZhangMLMingxiu LiuJYJianghong Yue

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Overview

Analysis shows rising ischemic stroke burden from high LDL-C in China, implying urgent public health strategies are needed.

Key Points

  • Ischemic stroke deaths due to high LDL-C rose to 936,192 globally and 300,053 in China in 2021, highlighting increasing impact.
  • In China, DALYs attributable to high LDL-C surged by 126.94%, suggesting a growing health crisis related to stroke.
  • Joinpoint regression analysis revealed significant trends in stroke burden, with notable sex-based discrepancies seen.
  • Future projections estimate 1.86 million global deaths and 630,000 deaths in China due to ischemic stroke by 2046.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/68a36c210a429f797332fa19https://doi.org/10.3389/fneur.2025.1622361
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