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Observational analysis showed increased plasma renin levels with age in patients with arterial hypertension, indicating gender differences are significant.
The article presents the results of a study on the age-related dynamics of plasma renin levels in healthy individuals and patients with arterial hypertension, including both men and women in different age groups: young adults (25–44 years), middle-aged adults (45–59 years), and older adults (60 years and older). The study revealed the following pattern: with age, healthy men and women showed a progressive and significant decrease in plasma renin levels compared to the young adult group. In contrast, patients with arterial hypertension demonstrated a significant increase in renin levels with age. The age-related trend in plasma renin levels was similar in men and women but was more pronounced in men.
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Вебер et al. (2025) studied this question.
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